Karmactive Staff
Vitruvias Therapeutics has recalled one lot of its Thyroid Tablets USP, 30 mg, because the product may be superpotent, meaning it may contain more thyroid hormone than its label states. The recall covers one lot only. The FDA has published a safety announcement about the recall.
The recalled lot is lot 504950, with NDC 69680-166-00 and an expiration date of September 30, 2026. The FDA notice states that 3,655 bottles were distributed nationwide between January 31, 2025, and September 30, 2025. The tablets are porcine-derived, meaning they are made from pig thyroid glands, and contain levothyroxine and liothyronine.
Why superpotency matters
Superpotency is the opposite of subpotency, in which a tablet contains less medication than its label states. Both conditions matter for patients who rely on precise dosing. Natural desiccated thyroid products are made from animal thyroid glands and are used by some patients with an underactive thyroid.
Porcine thyroid products are naturally derived. Batch-to-batch variation in potency in these products can leave narrower therapeutic margins than synthetic levothyroxine alone.
Taking superpotent thyroid hormone tablets can induce toxic hyperthyroidism. Excess thyroid hormone can produce symptoms of an overactive thyroid, including heart palpitations, a racing pulse, excessive sweating, heat intolerance, unexplained shakiness, muscle weakness, and nervousness. In vulnerable individuals, the excess may lead to life-threatening cardiac arrhythmias.
Patients who notice a rapid heart rate or excessive sweating may wonder whether their thyroid pills are responsible.
What patients should check
Patients should check their bottle label for the manufacturer name, Vitruvias Therapeutics, NDC 69680-166-00, and lot 504950. Because the recall covers one lot, the lot number is the key detail on the label. Patients whose bottles match the recalled lot are advised to contact their physician immediately about an adjusted replacement before taking their next dose.
Sudden chest tightness, a severe irregular heartbeat, or other serious symptoms call for urgent emergency medical evaluation.
Recall details
Patients who are unsure whether their bottle matches the recall can compare the NDC and lot number on the label with the values listed above. Details on the affected lot and its distribution have been published in the FDA safety announcement.
