The Dawn of a New Era in Cancer Treatment: The Story of AOH1996

City of Hope scientists discovered AOH1996, a game-changer in combating solid cancer tumors.

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At the heart of the scientific breakthrough is PCNA, a protein that has long been integral to cancer's proliferation, assisting in their repair and growth.

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AOH1996, the revolutionary molecule selectively disrupts DNA replication and repair in cancer cells, targeting the cancerous variant of PCNA.

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This 'cancer-stopping' pill blocks cancer's path, selectively impeding cancerous cells while sparing healthy ones.

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This 'cancer-stopping' pill blocks cancer's path, selectively impeding cancerous cells while sparing healthy ones.

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In preclinical studies, AOH1996 showed effectiveness against 70 different cancer types.

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AOH1996 does not merely offer a universal solution to solid tumors; it also manages to do so without inducing toxicity, an issue commonly associated with cancer treatments.

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With promising preclinical results in hand, the researchers are forging ahead with a Phase 1 clinical trial in humans.

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