By Karmactive Staff

IIT Madras, in collaboration with IIT Mandi, has engineered plant cells to enhance anti-cancer drug production.

By Karmactive Staff

Photo Source: Google

Their focus was on the endangered species Nothapodytes nimmoniana, a source of the crucial drug Camptothecin.

By Karmactive Staff

Photo Source: Google

A genome-scale metabolic model for N. nimmoniana cells identified key enzymes, increasing Camptothecin yield five-fold.

By Karmactive Staff

Photo Source: Google

The project leaders, Ms. Murali and Dr. Ibrahim from IIT Madras, implemented enzyme overexpression strategies.

By Karmactive Staff

Photo Source: Google

Prof. Srivastava emphasized the integration of metabolic and bioprocess engineering for sustainable drug production.

By Karmactive Staff

Photo Source: Google

The breakthrough has implications for India, where cancer cases are expected to rise significantly by 2025.

By Karmactive Staff

Photo Source: Google

The research, published in Frontiers of Plant Science, was funded by SERB and the DST, Government of India.

By Karmactive Staff

Photo Source: Google

Dr. Masakapalli from IIT Mandi highlighted the project's potential for sustainable biomanufacturing.

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