Ozempic Trial: 36% Success in Type 1 Diabetes vs 0% with Placebo

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The 26-week study focused on Type 1 diabetes patients with obesity using automated insulin delivery systems – a growing demographic facing unique challenges.

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Patients taking Ozempic lost an average of 20 pounds while maintaining better blood sugar control – potentially addressing the complex issue of "double diabetes."

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"For a hundred years, we are fixated on insulin and insulin delivery...and there aren't really extra medications approved for type 1," explains lead researcher Dr. Viral Shah.

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How does Ozempic work differently from insulin? It mimics a hormone called GLP-1 that slows digestion, reduces liver sugar production, and improves insulin sensitivity.

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While insulin remains essential for Type 1 diabetes, Ozempic could become the first approved add-on medication to help those who also struggle with obesity.

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The risk of severe low blood sugar didn't increase with Ozempic – with only two cases reported in both treatment and placebo groups.

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Despite these promising results, the FDA hasn't approved Ozempic for Type 1 diabetes yet – larger trials are needed before it becomes widely available.

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Dr. Ahmad Haidar from McGill University called the study "an important stepping stone" but cautioned that "we need more evidence" for regulatory approval.

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Could this be the first significant treatment advance beyond insulin in a century for Type 1 diabetes patients? Researchers hope pharmaceutical companies will now conduct larger approval trials.

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